Bone Marrow Transplant (BMT)

Inpatient and post-transplant management with high success rates.

A Bone Marrow (or Stem Cell) Transplant replaces diseased or treatment-damaged marrow with healthy stem cells. It’s used in select leukaemias, lymphomas, myeloma, marrow failure syndromes, and some immune disorders.

When BMT Is Considered

• Disease not responding fully to first-line treatment.
• High-risk leukaemia genetics.
• Relapsed lymphoma or myeloma
• Severe aplastic anemia.
• Certain inherited marrow or immune disorders.

Pre-Transplant Evaluation

Dr. Joshi helps patients through the exhaustive workup required: performance status, donor matching (HLA typing), infectious disease screening, organ function testing, psychological readiness, caregiver planning, and financial counselling.

Treatment Pathway

• Autologous BMT – patient’s own stem cells collected, stored, and reinfused after high-dose therapy (common in myeloma, some lymphomas).
• Allogeneic BMT – donor stem cells (matched sibling, unrelated, haplo-identical) used to restore marrow and deliver graft-vs-cancer benefit.
• Conditioning regimens – high-dose chemo +/- radiation to eliminate diseased marrow.
• Engraftment monitoring – daily counts, infection watch, transfusion support.
• GVHD (Graft vs Host Disease) surveillance & management in allogeneic transplants.
• Long-term follow-up – immune reconstitution, vaccination schedules, late toxicities.

How Dr. Joshi Supports Patients

Some centres perform the transplant; Dr. Joshi’s role includes selection, referral, peri-transplant coordination, and post-transplant clinical follow-up—crucial for detecting complications early and keeping recovery on track.